There is significant adoption of innovative technology in biotechnology which contributes to the global downstream processing market. Downstream processing refers to the purification and recovery of biosynthetic products, especially in pharmaceuticals from living organisms which includes tissues of animals or plants or fermentation broth. Downstream processing includes the recycling of those components that can be retrieved along with the treatment of disposal of wastage. It is helpful in the manufacturing of antibodies (infliximab and abciximab), antibiotics, natural hormones that are useful in the development of human growth, preparing insulin, vaccine, flavor, natural fragrance compounds, and in the production of industrial enzymes. The global rise in lethal diseases such as dengue, hepatitis, cholera, swine flu and so on will increase the demand for effective vaccination for these fatal diseases.

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The growing biotechnology sector is the major factor propelling the demand for the market. The rise in the downstream processing market is also attributed to the high adoption of biotech processing majorly in the agricultural, pharmaceutical and bio service. Rising demand for the high yield variety of seeds and other advancement is due to the development in the field of genetic engineering and gene therapy. Major players of global downstream processing industry endeavor to streamline the process and try to cut down the overall cost associated with the procedural cost and raw material which will ultimately reduce the overall price of the products.

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R&D investments are on the rise and the evolution of new downstream processing technology will further help in the development of the market. However, product life degradation, regulatory directives, and strict licensing policies can be a restraint for the downstream processing market. Major downstream processing techniques include member affinity chromatography, employment of high throughput process development, perfusion chromatography, and single-use systems. Moreover, growing investment in the development of bioprocess and fermentation technology for supporting large level production of biologics and biosimilar is expected to boost the growth of the downstream processing market.

Scope of inducing downstream processing technique for the commercial production of the biodegradable material has been increasing, owing to the development of the biosimilar. Contract Manufacturing Organizations (CMOs) are playing a distinctive role in the overall development of the market. A new pharma plant, that is equipped with the large stainless-steel bioreactor to produce large-volume biopharmaceuticals is expensive and time-consuming. Therefore, new market entrants, including startups and some large companies in their expansion programs are switching to CMOS rather than acquiring their own production house.

Current Market Trends Covered in the Report

• Rising incidence and prevalence rate of dengue, hepatitis, cholera, swine flu and so forth will create demand for the effective vaccination bolstered by downstream processing market.
• The rapid progress of the biotechnology sector is the major factor propelling the demand for the downstream processing market.
• R&D in the process to streamline the process of downstream and also to make it cost-effective.
• New entrants, including startups and some large companies in their expansion programs, are switching to CMOS rather than acquiring their own production house.
• North America (Comprising the US and Canada) is expected to hold the largest share in the global downstream processing market, followed by Europe.

Global Downstream Processing Market: - Segmentation

By Product

• Chromatography Columns and Resins
• Filters
• Single-Use Products
• Membrane Absorbers
• Others (Consumables and Accessories)

By Application

• Monoclonal Antibody (MABS) Production
• Insulin Production
• Vaccine Production
• Others (Immunoglobulin Production, Erythropoietin Production)

Global Downstream Processing Market: - Region

North America

• US
• Canada

Europe

• Germany
• UK
• Spain
• Italy
• France
• Rest of Europe

Asia-Pacific

• China
• Japan
• India
• Rest of Asia-Pacific

Rest of the World

• Middle East & Africa
• Latin America


Company Profiles

• 3M Co.
• Asahi Kasei Medical Co., Ltd.
• Batavia Biosciences B.V.
• Boehringer Ingelheim International GmbH
• Corning Inc.
• Eppendorf AG
• ESI Technologies Group
• Fenner Group Holdings Ltd.
• Flowserve Corp.
• FUJIFILM Diosynth Biotechnologies U.S.A., Inc.
• General Electric Co.
• Kaneka Corp.
• Lonza Group Ltd.
• Merck KGaA
• Parker Hannifin Corp.
• Repligen Corp.
• Sartorius AG
• Teva Pharmaceutical Industries Ltd.
• Thermo Fisher Scientific Inc.

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Downstream Processing Market by Technique,by Product, by Application – Global Trends, Industry Size, Share, Growth, and Forecast, 2019-2025