The North American oncolytic virus therapy market is estimated to grow at a CAGR of more than 16% during the forecast period. The market growth is attributed to the established research environment for various biotechnologies, the presence of major healthcare providers and growing healthcare investment in the US and Canada. Moreover, a growing number of cancer patients is augmenting the demand for oncolytic virus therapy. T?Vec (talimogene laherparepvec), is a recently approved oncolytic virus drug in the US and Europe. It is the second-generation oncolytic drug armed with GM-CSF to cure cancer.

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Research is undergoing other oncolytic virus drugs to cure cancer patients suffering from brain tumors along with breast, lung, liver and bladder cancer. There are other oncolytic virus drugs being researched which include JX?594 (pexastimogenedevacirepvec) for hepatocellular carcinoma, GM?CSF?expressing adenovirus CG0070 for bladder cancer, and Reolysin (pelareorep), a wild?type variant of reovirus for head and neck cancer.

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The North America oncolytic virus therapy market is segmented into the US and Canada. The US holds the highest market share in the North American market. The major share of the US market is attributed to the FDA approval of the Imlygic therapy by Amgen Inc., that received approval in the US in 2015. In addition, the increasing prevalence of melanoma further contributes to the growth of the market in North America.
Further, the North American oncolytic virus therapy market is segmented on the basis of product and application. Based on the product, the market is segmented into HSV-based oncolytic viruses, adenoviruses-based oncolytic viruses, vaccinia virus-based oncolytic viruses, vesicular stomatitis virus-based oncolytic viruses, Newcastle disease oncolytic viruses, and other oncolytic viruses. HSV-based oncolytic virus therapy held the highest market share of over 94% in 2018, whereas, adenoviruses-based therapy held the rest. Based on the application, the market is segmented into prostate cancer, breast cancer, ovarian cancer, melanoma, and others. In 2018, the melanoma application held the largest market share.

The report covers the analysis of several players operating in the North American oncolytic virus therapy market. Some of the major players include Bristol-Myers Squibb Company, Abbvie Inc., Janssen Biotech Inc., Cold Genesys Inc., Cynvec LLC, and others. In December 2018, Bristol-Myers Squibb Company signed an agreement with PsiOxus Therapeutics, Ltd. to grant the company rights to NG-348, a pre-clinical stage, an armed oncolytic virus which addresses solid tumors. PsiOxus developed tumor-targeted delivery with oncolytic viruses’ platform, to target cancer and enable more patients to respond to treatment. The company has continued the study and development of immuno-oncology, which includes development in NG-348, in order to understand the potential of oncolytic viruses to boost checkpoint blockade in several types of cancer.

North American Oncolytic Virus Therapy Market Segmentation

By Product

• HSV-Based Oncolytic Virus
• Adenoviruses-Based Oncolytic Virus
• Vaccinia Virus-Based Oncolytic Virus
• Vesicular Stomatitis Virus-Based Oncolytic Virus
• Newcastle Disease Virus- Based Oncolytic Virus
• Others

By Application

• Prostate Cancer
• Breast Cancer
• Ovarian Cancer
• Melanoma
• Others

Regional Analysis

• US
• Canada

Company Profiles

• AbbVie, Inc.
• Amgen, Inc.
• Bristol-Myers Squibb Company
• Cold Genesys Inc.
• Creative Biolabs Inc.
• Cynvec LLC
• DNAtrix Inc.
• Genelux Corp.
• Janssen Biotech Inc.
• Merck & Co., Inc.
• Oncolytic Biotech, Inc.
• Oncorus Inc.
• Sorrento Therapeutics Inc.
• Vyriad

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