Global Antisense and RNAi Therapeutics Market was valued US$ X1.2X Bn in 2019 and is expected to reach US$ XX Bn by 2027, at CAGR of X7.XX% during forecast period of 2020 to 2027.

Global Antisense and RNAi Therapeutics Market: Overview

In past years, pharmaceutical companies were motivated about the prospective of RNA interference (RNAi). But later, financial volatility and subsequent suspensions by pharmaceutical companies have articulated that RNAi therapeutics market was fiished. Yet, advances in nano medicine helped the vast potential of RNAi therapeutics to flourish. Antisense technology offers the prospect to influence the gene expression and this is being considered as an effective treatment for various diseases. Based on this factor, great number of gene silencing drugs are in the development process.

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The global antisense and RNAi therapeutics market have gathered substantial attention in the recent years, due to its perspective to treat many sort of chronic diseases such as tuberculosis, diabetes, cancer, AIDS, as well as certain cardiovascular problems. This prospect is being cashed on by the many companies in this industry and are investing in R&D. Just to emerge as being in the clinical research division, the RNA based therapeutics are likely to be explored as a most efficient treatment choice for the disorders, which are very difficult to treat. Market is expected to grow at CAGR XX.XX% over the forecast period, as number of companies are into the development of molecules focused on antisense technology.

However, there are many challenges associated with the emerging antisense technology and RNAi. One of the noticeable issue is the drug delivery to the proposed portion. Drug delivery to the nervous tissues is one of the problems as the drug has to pass the blood-brain barrier. Major players in the industry are coming up with solutions to overcome these challenges.

The other challenge is toxic effects caused by the use of this technology. Determining the right dosage and path for drug delivery of an antisense molecule is one of the most crucial process to ensure the safe administration. While overcoming this as much as possible and implementing it, companies have encountered multiple rejections from the regulatory bodies. For instance, FDA has refused, an antisense molecule to treat familial chylomicronemia syndrome by the renowned U.S. organization Akcea’s Waylivra. Such events would push companies to develop better paths, efficient delivery solutions, and effective compositions.

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