Meticulous Research®—a leading global market research company—has published its latest research report titled “Protein Expression Market by System (Mammalian [CHO, HEK 293], Non-mammalian [Bacterial, Insect, Yeast]), Offering (Kits & Reagents, Vectors, Competent Cells, Services), Application (Industrial, Therapeutic, Research), and End User - Global Forecast to 2030.”

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The report forecasts that the protein expression market will reach $5 billion by 2030, growing at a CAGR of 7.6% during the forecast period. Key factors driving this growth include the expanding biopharmaceutical market, increasing demand for recombinant proteins, and a rise in cell-based research. Additionally, the prevalence of chronic diseases, advancements in molecular and cellular technologies that enhance bioproduction, and increased government initiatives for life science research are significant contributors to market expansion. Emerging economies and the rise of point-of-care (POC) technology present further opportunities for growth.

However, the market faces challenges such as the high costs associated with protein-based research and a lack of skilled professionals. Additionally, complexities in laboratory transformation parameters may hinder market progress.

Market Segmentation and Future Outlook

The protein expression market is categorized by system type (mammalian and non-mammalian cell expression systems, cell-free expression systems), products and services (instruments, kits & reagents, competent cells, expression vectors, and services), application (therapeutic, industrial, research), end user (pharmaceutical and biotechnology industries, academic and research institutes, and contract research organizations), and geography.

In 2024, the mammalian cell expression system segment is expected to dominate the market due to its alignment with human physiology, facilitating post-translational modification and minimizing cross-contamination risks. The kits and reagents segment is anticipated to hold the largest share among products and services, driven by their repetitive usage in protein-based research and transfection processes.

Therapeutic applications are projected to account for the largest share in 2024, reflecting the increasing focus on therapeutic protein research and government efforts to streamline approval processes. The pharmaceutical and biotechnology industry is also expected to lead in market share, supported by heightened proteomics research and governmental initiatives aimed at expediting recombinant protein production.

Geographic Review

The report provides a comprehensive analysis of major regions, including North America (U.S. and Canada), Europe (Germany, France, U.K., Italy, Spain, and Rest of Europe), Asia-Pacific (China, Japan, India, and Rest of Asia-Pacific), Latin America, and the Middle East & Africa. North America is projected to maintain the largest market share in 2024, driven by high R&D expenditures and the presence of key market players. The U.S. is expected to lead this region's market due to its advanced research capabilities.

Key Market Players

Prominent players in the protein expression market include:

Thermo Fisher Scientific Inc. (U.S.)
Promega Corporation (U.S.)
Merck KGaA (Germany)
Bio-Rad Laboratories, Inc. (U.S.)
Takara Holdings Inc. (Japan)
GenScript Biotech Corporation (U.S.)
Qiagen N.V. (Germany)
Agilent Technologies, Inc. (U.S.)
Danaher Corporation (U.S.)
Becton, Dickinson and Company (U.S.)
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