The global hypertrophic cardiomyopathy (HCM) therapeutics market is estimated to grow at a CAGR of nearly 1.5% during the forecast period. The significant prevalence of CVD is the major factor contributing to the market growth. As per the World Health Organization (WHO), CVDs are the major cause of mortality across the globe. In 2016, CVD accounted for nearly 17.9 million mortalities, which represented 31% of all global mortalities. 85% of these mortalities were reported due to stroke and heart attack. HCM is a genetic cardiac disease, which occurs due to the increase in wall thickness of left ventricle. It is usually caused by abnormal genes in the heart muscle, which cause left ventricle walls to become thicker and harder than normal.

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Each child of a person with HCM has a 50% chance of inheriting the condition. In UK, nearly 1 in 500 people have the condition, however, most people who are suffering from this condition have few symptoms. The objective of HCM treatment is to provide relief from symptoms and avoid sudden cardiac death in people who are at high risk. Medications can support to slow the heart rate that facilitates the heart to pump blood better. The medications that are used for the treatment of HCM and its symptoms may comprise calcium channel blockers, beta-blockers, antiarrhythmic drugs, and anticoagulants. However, these medications have certain side-effects that may comprise low blood pressure and fluid in the lungs and in some cases, certain medications may cause sudden death. The increasing demand for surgeries such as septal myectomy, septal ablation, heart transplant, and implantable cardioverter defibrillator, to treat HCM is further expected to hinder the market growth.


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Antiarrhythmic agents enable to block irregular electrical activity, which in turn, supports the heart to beat normally. These medications can also support to prevent abnormal heart rhythms that occur due to the thickness of the heart’s walls. Sotolol (BetaPace) is considered as a useful drug for people suffering from arrhythmias. This drug may reduce blood pressure and seems to have some side effects. Additionally, Amiodarone (Cordarone) is the most commonly anti-arrhythmic drugs for HCM treatment that appears as a potent drug. However, it has several potentially severe side effects, such as hyperthyroidism, pulmonary toxicity, liver function abnormalities, proarrhythmia, and optic neuropathy, which can lead to blindness.

Global Hypertrophic Cardiomyopathy (HCM) Therapeutics Market Segmentation
Global HCM Therapeutics Market by Drug Class
• Beta Adrenergic Blocking Agents
• Anticoagulants
• Antiarrhythmic Agents
• Calcium Channel Blockers
• Others


Global Hypertrophic Cardiomyopathy (HCM) Therapeutics Market – Segment by Region
North America
• United States
• Canada

Europe
• Germany
• United Kingdom
• France
• Spain
• Italy
• Rest of Europe

Asia-Pacific
• China
• Japan
• India
• Rest of Asia-Pacific

Rest of the World
• Latin America
• Middle East and Africa

Company Profiles
• Menarini Farmaceutica Internazionale srl
• ANI Pharmaceuticals, Inc.
• AstraZeneca plc
• Bayer AG
• Bristol Myers Squibb Co.
• Cipla Ltd.
• General Electric Co.
• Gilead Sciences, Inc.
• Lannett Co., Inc.
• Merck & Co., Inc.
• Mylan N.V.
• MyoKardia, Inc.
• Novartis International AG
• Pfizer Inc.
• Sanofi S.A.


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