Meticulous Research®—a leading global market research company, published a research report titled, ‘Protein Expression Market by System (Mammalian [CHO, HEK 293], Non-mammalian [Bacterial, Insect, Yeast]), Offering (Kits & Reagents, Vectors, Competent Cells, Services), Application (Industrial, Therapeutic, Research), and End User - Global Forecast to 2030.’

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According to this latest publication from Meticulous Research®, the protein expression market is projected to reach $5 billion by 2030, at a CAGR of 7.6% during the forecast period. The increasing biopharmaceutical market, growing demand for recombinant proteins, increasing cell-based research, growing number of chronic diseases, improvements in molecular & cellular technology to speed up bioproduction, and rising government initiatives and funding for life science research are driving the growth of this market. Furthermore, the potential emerging economies and the emergence of POC technology are expected to offer significant growth opportunities for the protein expression market.

However, the high cost of protein-based research and the lack of skilled professionals is expected to restrain the growth of this market. Additionally, complexities in laboratory transformation parameters are challenging the growth of this market.

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Protein Expression Market: Future Outlook

The protein expression market is segmented based on System Type [Mammalian Cell Expression System (Chinese Hamster Cell Lines, HEK 293 Cell Lines, and Others), Non-mammalian Cell Expression System (Bacterial Cell Lines, Insect Cell Lines, Yeast Cell Lines, Plant Cell Lines, and Algal-based Cell Lines), Cell-free Expression System], Product & Services [Instruments, Kits & Reagents, Competent Cells (Chemically Competent Cells and Electrocompetent Cells), Expression Vectors, and Services], Application (Therapeutic, Industrial, and Research), End User (Pharmaceutical and Biotechnology Industry, Academic and Research Institutes, and Contract Research organizations), and Geography. The study also evaluates industry competitors and analyzes the market at the regional and country levels.

Among the system type, in 2023, the mammalian cell expression system segment is expected to account for the largest share of the protein expression market. The large market share of this segment is attributed to wide acceptance due to their resemblance with human physiology, thereby reducing efforts for post-translational modification and cross-contamination. Also, increasing cell-based and therapeutic protein production, low cost & ease of use of mammalian expression system supported the share.

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Based on product and services, the protein expression market is segmented into Instruments, Kits & Reagents, Competent Cells, Expression Vectors, and Services. In 2023, the kits and reagents segment is expected to account for the largest share of the recombinant coagulation factors market. The growth of this segment is attributed to its repetitive use. Moreover, the increasing number of protein-based research and the continuous need for transfection, correct folding of proteins in research, and expanding biopharma market supported the growth.

Based on application, the protein expression market is segmented into therapeutic, industrial, and research. In 2023, the therapeutic segment is expected to account for the largest share of this market. The large share of this segment is attributed to the growing development of therapeutic protein-based research and government initiatives for reducing lengthy approval time.

Based on end user, the protein expression market is segmented into pharmaceutical and biotechnology industry, academic and research institutes, and contract research organizations. In 2023, the pharmaceutical and biotechnology industry segment is expected to account for the largest share of this market. The large share of the pharmaceutical and biotechnology industry segment is attributed to the rising proteomics research and companies' participation in recombinant protein production due to the government's focus on reducing approval time.

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Geographic Review

This research report analyzes major geographies and provides comprehensive market insights into North America (U.S. and Canada), Europe (Germany, France, U.K., Italy, Spain, and Rest of Europe), Asia-Pacific (China, Japan, India, and Rest of Asia-Pacific), Latin America and the Middle East & Africa.

In 2023, North America is expected to account for the largest share of the protein expression market, followed by Europe and Asia-Pacific. Furthermore, in 2023, the U.S. is expected to account for the largest share of the North America market. The large share of this market is attributed to the high R&D expenditure and presence of key market players.

Key Players

The key players operating in the protein expression market are Thermo Fisher Scientific Inc. (U.S.), Promega Corporation (U.S.), Merck KGaA (Germany), Bio-Rad Laboratories, Inc. (U.S.), Takara Holdings Inc. (Japan), GenScript Biotech Corporation (U.S.), Qiagen N.V. (Germany), Agilent Technologies, Inc. (U.S.), Danaher Corporation (U.S.), and BECTON, DICKINSON AND COMPANY (U.S.).

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