The global nucleic acid isolation and purification market is estimated to grow at a CAGR of more than 8.0% during the forecast period. The major factors contributing to the growth of the market include a significant rise in cancer incidences and increasing demand for precision medicine. As per the World Health Organization (WHO), in 2018, the cancer burden across the globe is anticipated to have increased to 18.1 million new incidences and 9.6 million mortalities. Globally, one in 5 men and one in 6 women develop cancer in their lifetime. Globally, there were 43.8 million patients suffering from cancer in 2018.
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In 2018, Europe held 23.4% of the global cancer incidences and Americas account for 21.0% of the global cancer incidences. In Asia and Africa, the proportion of cancer mortalities were 57.3% and 7.3%, respectively, which is higher as compared to the proportion of incident cases, 48.4% and 5.8%, respectively. Molecular biology is one of the tools used for cancer diagnosis and treatment. It studies the structure, composition, and interactions of cellular molecules including proteins and nucleic acids. Molecular tests based on DNA methylation can support to assess the toxic effects of chemotherapy. Among cancer patients, the adequate screening, diagnosis, prognosis, and response to treatment are necessary to ensure the most potent therapy.
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The first step in most molecular biology is purification or isolation of nucleic acids. There is a range of methods available for nucleic acid extraction and purification and researchers normally opt for the method that is most appropriate to their downstream applications, target nucleic acid, source organism, and desired results. Solvent extraction is normally utilized to remove contaminants from nucleic acids. Nucleic acid purification products are optimized to offer maximum yield, integrity, and purity, while isolating nucleic acids from cancer-associated samples such as blood, tissue, and archived formalin-fixed, paraffin-embedded (FFPE) samples. It can efficiently be used to purify genomic DNA, RNA, and miRNA. Therefore, Nucleic acid isolation and purification methods have a crucial role in molecular biology applications for non-invasive diagnostics and disease management.

Market Segmentation
The global nucleic acid isolation and purification market is segmented based on method, product, type, application, and end-user. Based on the method, the market is classified into the column based, magnetic beads, reagent based, and others. Based on the product, the market is classified into reagents and kits, and instruments. Based on type, the market is classified into DNA and RNA. Based on application, the market is classified into precision medicine, oncology, drug discovery and development, agricultural and animal research, diagnostics, and others. Based on end-user, the market is classified into hospitals and diagnostic centers, pharmaceutical and biotechnology companies, contract research organizations, and others.

Column-based nucleic acid isolation and purification is anticipated to hold significant share in the method segment
In 2018, Column-based nucleic acid isolation and purification is estimated to witness potential share in the method as it is used to quickly purify nucleic acids. Column based DNA extraction kit is designed for faster extraction and purification of pure genomic DNA from the whole blood. The method has several advantages as compared to other crude methods of DNA extraction and doesn’t contain harmful organic compounds including chloroform and phenol. The kits use a spin-column and chaotropic salts for binding of nucleic acids to an activated glass filter with a potential high binding capacity.

Regional Outlook
The global nucleic acid isolation and purification market is segmented based on four major regions, including North America, Europe, Asia-Pacific, and Rest of the World (RoW). In 2018, North America is estimated to hold a significant share in the market owing to the rising prevalence of chronic diseases and significant drug discovery and development activities in the region. As per the Eurostat, in 2018 North America held 48.9% of the global pharmaceutical sales than 23.2% for Europe. The has led by the increasing drug discovery and development activities in North America. This, in turn, contributes to the demand for nucleic acid isolation and purification technique to rapidly identify a significant number of target genes and evaluate disease vulnerability and drug response.

Market Players Outlook
The major players operating in the market include F. Hoffman La-Roche AG, Thermo Fisher Scientific Inc., Illumina, Inc., QIAGEN N.V., and Purigen Biosystems, Inc. These companies are using several strategies, including mergers and acquisitions, product launches, and partnerships and collaborations, to expand market share and gain a competitive advantage. For instance, in April 2020, Thermo Fisher Scientific and Hamilton Company launched nucleic acid extraction platform for forensic laboratories. NIMBUS Presto assay ready workstation is an easy-to-use and faster-automated DNA sample preparation system which is intended for the extraction of nucleic acids from evidentiary crime scene samples.

By combining the liquid handling capability of Hamilton with nucleic acid purification strategy of Thermo Fisher Scientific using PrepFiler extraction chemistry and KingFisher magnetic-particle technology, Thermo Fisher has been able to minimize the sample preparation duration in forensic laboratories by up to 80%. This decrease in time enables DNA analysts to process samples of more crime scene quicker, allowing more rapid prosecutions.

The Report Covers
Market value data analysis of 2018 and forecast to 2025.
Annualized market revenues ($ million) for each market segment.
Country-wise analysis of major geographical regions.
Key companies operating in the global nucleic acid isolation and purification market. Based on the availability of data, information related to pipeline products, and relevant news is also available in the report.
Analysis of business strategies by identifying the key market segments positioned for strong growth in the future.
Analysis of market-entry and market expansion strategies.
Competitive strategies by identifying ‘who-stands-where’ in the market.
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