The global kainic acid market is expected to grow at a significant CAGR during the forecast period. Kainic acid is a cyclic analogue of L-glutamate that binds to ionotropic kainic acid receptors and acts as an agonist. It was isolated and extracted from digenea simplex, red algae occurring in tropical and sub-tropical water. It was originally known as digenic acid; however, the name was changed to kainic acid to prevent confusion with other digenea derivatives. Kainic acid was developed as an ascaricide to treat ascariasis, a disease caused by ascaris lumbricoides. The temporal lobe epilepsy model based on kainic acid has significantly supported the understanding of the molecular, cellular, and pharmacological mechanisms underlying epileptogenesis and ictogenesis.

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Excitotoxicity plays a role in several central nervous system (CNS) neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis. Kainic acid (KA), an excitotoxic glutamate analogue, can cause selective neuronal death in rodents’ brains, with pathological alterations which mimic neurodegeneration in the CNS. As a result, KA-induced neurotoxicity in rodents has been used to investigate the pathogenesis of excitotoxicity in neurodegenerative diseases.

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The neuropathological and electroencephalographic properties of this model are similar to those found in patients with temporal lobe epilepsy. Epilepsy is the most common neurological condition, according to the World Health Organization (WHO), with a prevalence of over 50 million people and an annual incidence of 2.4 million. The most prevalent type of partial epileptic disorder is temporal lobe epilepsy (TLE), which accounts for 60% of all cases. This rising prevalence of epilepsy disorder around the globe is expected to drive the global kainic acid market.

Global Kainic Acid Market – Segmentation
By Type
Low Purity (Below 97%)
Purity (Above 97% and below 99%)
High Purity (Above 99%)
Others
By Application
Epilepsy Treatment
Neurological Research
Others

Global Kainic Acid Market – Segmentation by Region 
North America 
United States
Canada
Europe
Germany
United Kingdom
France
Spain
Italy
Rest of Europe
Asia-Pacific 
China
Japan
India
Rest of Asia-Pacific
Rest of the World

Company Profiles
Glentham Life Sciences
R&D Systems
Abcam plc

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