According to the CDC, in the U.S., the leading cause of death for women and men of most ethnic groups is heart disease, and every 36 seconds, one person dies from it. When the supply of oxygen-rich blood to the heart stops or decreases, coronary heart disease develops, which is one of the most-common CVDs and a key factor behind heart attacks. There are many reasons for heart diseases, including age, bad lifestyle choices, genetics, certain infections (such as untreated strep, which can cause rheumatic heart disease), and a few environmental factors, such as toxins.

The first step in lowering the incidence of CVDs is to improve diagnostics. With an ever-evolving understanding of the molecular changes linked to CVDs, particularly inherited heart disorders, there is an urgent need to identify effective and sophisticated diagnostic approaches, for minimizing the clinical burden imposed by such diseases. Therefore, healthcare settings are integrating molecular diagnostic tests for the evaluation of CVDs, to provide improved clinical insights and early treatment solutions.

Whereas regular cardiology mostly relies on diagnosing CVDs by studying the electrical impulses flowing through the cardiac muscle, via techniques such as EKG; ascertaining the efficiency of the blood flow via angiograms, or visualizing the functioning of the heart muscle or its structure from the outside, via CT, MRI, or echocardiograms, precision cardiology seeks to diagnose diseases and offer treatments targeted at the molecular level. For this, a variety of bodily fluids, such as blood, saliva, and buccal swab, are extracted and their molecular contents analyzed.

North America generated the highest revenue in the precision cardiology market in the past. The existence of large life sciences companies in the U.S., as well as the widespread use of innovative services and goods in clinical practice and research, is credited for this. Furthermore, the government measures aimed at correlating genetic indicators with cardiovascular treatment have boosted the region's overall cardiology field. Furthermore, the FDA and the Clinical Laboratory Improvement Amendments (CLIA) have played a vital role in developing rules and regulations for the use of precision medical services in the country.

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