Bone Graft And Substitutes Market Size And Forecast

Bone Graft And Substitutes Market size was valued at USD 3.02 Billion in 2020 and is projected to reach USD 4.61 Billion by 2028, growing at a CAGR of 5.54% from 2021 to 2028.

With a rise in the global geriatric population, the number of orthopedic surgeries is expected to grow. Also, the increasing number of spinal fusion surgeries, target population, and adoption of allografts are driving the growth of the market for this market. The Global Bone Graft And Substitutes Market report provides a holistic evaluation of the market. The report offers a comprehensive analysis of key segments, trends, drivers, restraints, competitive landscape, and factors that are playing a substantial role in the market.

Global Bone Graft And Substitutes Market Definition

Bone grafting is a surgical procedure that includes the replacement of missing bone. Different types of bone grafts such as autologous bone graft, allograft, and synthetic bone graft are used in bone grafting procedures. The incorporation of bone graft can be defined as a procedure of interdigitation and envelopment of the donor bone tissue with the new bone deposited by the recipient. It is versatile that replaces the lost bone tissue, enhances bone growth using natural mechanisms. Natural bone grafts are the most successful types of bone grafts and are considered to be the gold standard for the replacement of missing bones.

Bone grafts are used for various purposes such as to fill the cavities resulting from cysts, tumors, or other causes, to stimulate the healing of fractures that have failed to heal after an initial treatment attempt, and others. Bone grafts are widely adopted in orthopedic surgeries. These surgeries are classified as elective surgeries and most of the elective surgeries were postponed or canceled during the Covid-19 pandemic. This resulted in a drastically decreasing demand for devices required for orthopedic surgeries, including bone graft & substitutes. Furthermore, extended factory closures by market players in various nations also slowed down the production of the devices.

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Bone grafting is a scientific term that involves surgical procedures by which broken bones i.e. fractures or holes in bones are healed by replacement material. The process is been practiced in order to treat bone defects that are extremely complex and possess significant health risks to patients, delayed union or non-union, and spinal fusion in orthopedic clinically for a period of time, despite the emergence of synthetic bone graft substitutes. However, the combination of allogeneic grafts and synthetic substitutes with host bone has been found to possess a threat in the long term. Hence, the process is often followed by osteointegration of these grafts and substitutes.

Global Bone Graft And Substitutes Market Overview

The increasing prevalence of bone cancer is expected to drive Global Bone Graft And Substitutes Market growth. The rising prevalence of bone cancer is expected to fuel demand for bone grafts and substitutes thereby supporting the Global Bone Graft And Substitutes Market growth over the forecast period. For instance, according to 2017 American Society of Clinical Oncology (ASCO) estimates, around 3,450 people of all ages in the U.S. were diagnosed with primary bone cancer. Thus, new cases of bone cancer are expected to propel the growth of the bone cancer treatment market in the U.S.

In addition, the rising adoption of dental bone grafts boosting the market growth. The higher success rate associated with dental bone grafts is boosting their demand. Minim Invasive Surg in 2018, stated that minimally invasive procedures were adopted for the treatment of a varied range of bone disorders in the year. It also stated that about 400,000 spinal fusion cases were done in the U.S. annually. Such factors positively impact market growth. Furthermore, the increasing trend of adoption of minimally invasive surgeries (MIS) is further boosting the demand for bone grafts & substitutes market.

The minimally invasive procedures come with several advantages such as minimal pain, reduced post-operative duration, and less injury to the tissue. Thus, medical professionals are preferring MIS rather than open surgery. Moreover, technological advancements in the implementation of human growth factors into bone grafts that has osteoconductive and osteoinductive properties such as demineralized bone matrix, bone morphogenetic proteins, and platelet-rich plasma (PRP), are expected to offer growth opportunities for market players to establish a strong position in the Global Bone Graft And Substitutes Market over the forecast period.

Researchers are focused on developing innovative bone grafts for treating bone-related disorders. For instance, in 2015, scientists at Texas A&M University developed a new synthetic material- a biodegradable scaffold to fill the gaps for new bone growth to advance grafting treatments required by the people for treating bone defects and bone cancers. However, there are certain restraints and challenges faced which will hinder the overall Bone Graft And Substitutes Market growth. The high cost associated with surgeries and ethical issues related to bone grafting procedures is expected to limit the growth of this market.

Global Bone Graft And Substitutes Market Segmentation Analysis

The Global Bone Graft And Substitutes Market are segmented on the basis of Type, Application, And Geography.

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Bone Graft And Substitutes Market, By Type

• Allograft
• Bone Graft Substitute
• Cell-based Matrices

Based on Type, the market is bifurcated into Allograft, Bone Graft Substitute, and Cell-based Matrices. Allograft held the largest revenue share in the past and is likely to dominate the market during the forecast period. The market is expected to grow at a significant rate during the forecast period because of properties such as quick structural support and osteoconductivity. Also, Allografts do not need multiple surgeries to harvest bone, which leads to reduced surgery time and quick wound healing. Thus, allografts are most commonly used in areas such as the spine, hip, and knee.

Bone Graft And Substitutes Market, By Application

• Craniomaxillofacial
• Dental Bone Grafting
• Joint Reconstruction
• Spinal Fusion
• Trauma

Based on Application, the market is bifurcated into Craniomaxillofacial, Dental Bone Grafting, Joint Reconstruction, Spinal Fusion, and Trauma. The Spinal Fusion accounts for the largest revenue share. Spinal fusion is used to correct defects in small bones in the spine. The rise in the elderly population suffering from spinal deformities and disorders leads to the rising adoption of spinal grafting procedures as a treatment method is anticipated to boost the revenue over the forecast period.

Bone Graft And Substitutes Market, By Geography

• North America
• Europe
• Asia Pacific
• Rest of the world

On the basis of Geography, the market is bifurcated into North America, Europe, Asia Pacific, and the Rest of the world. North America led the global market in 2019 and accounted for over 41% share of the overall revenue. Growing awareness about the commercially available advanced products, rising healthcare expenditure, and accessibility of a well-developed healthcare structure are the major aspects contributing to the region’s growth. The U.S. is the top revenue-generator in the North American regional market due to high product demand on account of the rising incidence rate of orthopedic diseases and trauma-related injuries.

Key Players

The “Global Bone Graft And Substitutes Market” study report will provide a valuable insight with an emphasis on the global market including some of the major players such as Arthrex, Inc., Baxter International Inc., Integra LifeSciences Holdings Corporation, Johnson & Johnson (DePuy Synthes), Medtronic Plc., Musculoskeletal Transplant Foundation, NuVasive, Inc., Stryker Corporation, Wright Medical Group N.V., and Zimmer Biomet Holdings, Inc.

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