The global bone graft substitute market is expected to touch USD 5,031 million at a stellar 6.52% CAGR over the forecast period (2017-2027). Simply put, bone graft is an implantable material that helps in promoting bone healing, osseous reconstruction and bone formation owing to its osteoinductive, osteogenic and osteoconductive properties. Bone graft is used in spinal surgery, sports, trauma plastic and facial surgery. Besides it can be used for filling the voids during absence of bones and structural stability.

It is a surgical method to replace a defected or missing bone using bone graft from the body of the patient, another person, animals or cadaver. Bone graft is also used to heal wounds, treat complex fracture and others. There are many factors that is driving the growth of the bone graft substitute market size.

Some of these factors as per the Market Research Future (MRFR) report include increasing incidence of musculoskeletal disorders, advancements in technology in the medical sector resulting in shift to allograft from autograft, development of the biocompatible synthetic bone grafts, rising demand for the dental bone grafts, key players laying emphasis on research and development activities both in bone grafts as well as its substitutes, increase in demand for orthopedic methods amid geriatric population, accessibility of advanced products in different sizes and shapes offering high osteoinductive and osteoconductive properties and shift to minimally invasive techniques.

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On the contrary, factors such as soaring cost of surgeries, ethical issues associated to bone grafting techniques, stringent regulatory pathway, unmet medical needs especially in low income countries, improper fixation, weak bonding, risk of graft rejection and patient safety owing to the danger of disease transmission in xenograft and allografts is likely to hamper the growth of the bone graft substitute market.

Key Players

Leading players profiled in the bone graft substitute market include Institut Straumann AG, Zimmer Biomet, Stryker Corporation, Medtronic plc, Dentsply Sirona, BioHorizons IPH, Inc, Dentium Co., Ltd., and ACE Surgical Supply Company, Inc.

Feb 2019- Sirakoss Ltd received CE mark clearance for its Osteo, the bone graft substitute which is nanosynthetic in nature intended to augment the healing of patients and offer surgeons with an advanced bone fracture solution. Osteo has specially been designed for supporting the skeletal system post corrective surgery of any deformity condition or completing bone regeneration following a fracture. This bone graft material will help in filling gaps in the skeletal system and can be used on its own or in combination with allograft or autograft.

Market Segmentation

Market Research Future report offers an all-inclusive segmental analysis of the bone graft substitute market on the basis type and application.

Based on type, it is segmented into bone morphogenetic protein, synthetic bone grafts, demineralized bone matrix, autograft and others.
Based on application, the bone graft substitute market is segmented into foot and ankle, dental, long bone, joint reconstruction, spinal fusion and others. Of these, spinal fusion is expected to have the maximum share in the market.
Regional Analysis

Based on region, the bone graft substitute market covers growth opportunities and latest trends across North America, Europe, Asia Pacific and Middle East and Africa. Of these, North America will dominate the market and hold its position during the forecast period at a favorable 6.1% CAGR. It is owing to factors such as advancements in technology in healthcare, existence of key players and others. US has a highly developed healthcare sector which is another key reason that is driving the bone graft substitute market in this region.

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Europe grabs the second largest position and is anticipated to grow at a healthy 6.76% CAGR due to rising awareness regarding bone graft substitutes coupled with increasing healthcare expenditure. The bone graft substitute market in the APAC region is expected to grow at 6.85% CAGR over the forecast period. The existence of fast developing economies like India and China are greatly supporting the market growth. On the other hand, the bone graft substitute market in the Middle East and Africa is anticipated to have a steady growth owing to developments in the Gulf nations’ healthcare sector.